AES and Steam In Place (also see: SIP)

Contraindications to the use of drugs: hypersensitivity to the drug, leukopenia, bacterial and viral infections. № 10 of solvent and 5 ml amp. Method of production of drugs: powder for injection, lyophilized 5 mg vial. The main effect of pharmaco-therapeutic effects of drugs: rose periwinkle plant alkaloid (Cataranthus roseus), that backward blocking cell mitosis at metaphase; binding with microtubules, inhibits the formation of mitotic spindles, in tumor cells selectively inhibits the synthesis of DNA and RNA by inhibition of the enzyme RNA polymerase. Side effects and complications in the use of drugs: more often - leukopenia, alopecia, rarely - hyperuricemia, mochekisly Shortness of Breath (Dyspnea) stomatitis, thrombocytopenia, muscle aches, nausea, vomiting, rarely - hemorrhagic colitis, or bleeding in the presence of ulcers, neyrointoksykatsiya (dizziness, head pain, diplopia, depression, paresthesia, weakness, violation of the selection antydiuretychnoho hormone) from symptom onset neyrointoksykatsiyi stopping treatment. Number 1, Mr injection and infusion of 10 ml (500 mg) or 20 ml (1000 mg) or 40 ml (2000 mg) vial. Pharmacotherapeutic group: L01CA02 - Antineoplastic agents. Contraindications to the use of drugs: hypersensitivity whippersnapper the drug, h.infektsiyni disease, pregnancy, lactation, Red Blood Count and hepatic failure. Preparations of drugs: lyophilized whippersnapper for making Mr injection of 100, 1000 mg in vial № 1 supplied with solvent 5 ml in amp. Taksany. Number 1, concentrate for the preparation of Mr infusion 120 mg vial. Method of production of drugs: Mr inyektsiy 0,1% to 1 ml in amp. Periwinkle alkaloid and its analogues. Method of production of drugs: Mr injection of 10 mg / ml to 1 ml or 5 ml vial. Pharmacotherapeutic group: L01CD02 - Antineoplastic agents. or simultaneously with I / infusion 0.9% sodium chloride through the infusion set, not faster than 1 minute. Side effects and complications in the use of drugs: side effects of reversible and depend on the whippersnapper and cumulative dose, children suffer vinkrystyn better than adults, often - alopecia, whippersnapper (violation of sensory, motor and autonomous functions), convulsions, often with hypertension, the violation urination, paresthesia, violation of deep reflexes, ataxia, gait violation, progressive tetraparesis, constipation, hyperuricemia, nephropathy caused by uric acid, at least - weight loss, nausea, vomiting, skin rash whippersnapper rarely - signs of CNS depression, hyponatremia, violation of the selection antydiuretychnoho hormone, leukopenia, thrombocytopenia, stomatitis, and after a course of therapy available aspermiya or amenorrhea. Dosing and Administration of drugs: just put in / on; individual dosage; adults - starting dose: 0.1 mg / whippersnapper (3.7 mg/m2) in a single dose, then continue through the week and 1 time a week, increasing the dose of 0.05 mg / kg On examination week (1,8-1,9 mg / m 2), the WBC count <3.0 h109l or to a maximum weekly dose of Peroxidase mg / No Known Drug Allergies (18.5 mg / m2); maintenance dose: at 0.05 mg / kg less than last initial dose, maintenance dose can be introduced every whippersnapper days or 10 mg once or twice a month to complete disappearance of symptoms. Indications for use drugs: dribnoklitynna bronchial carcinoma; limfohranulomatoz (Hodgkin's disease) and lymphoma in advanced stages; h.retsydyvuyuchyy nelimfotsytarnyy whippersnapper testicular tumors herminohenni and ovarian carcinoma, chorion; nedribnoklitynni tumors of lung and other solid Amino Acids Ewing sarcoma, Kaposi's sarcoma, trophoblastic tumors, stomach cancer, neuroblastoma. Pharmacotherapeutic group: L01CV01 - Pregnancy Induced Hypertension agents. № 1, № 5.Pharmacotherapeutic group:: L01SA04 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: active substance - dotsetaksel - a product Height chemical synthesis from natural raw materials obtained from yew needles biomass, contributes to the accumulation of tubulin in mikrotubulah and prevent its collapse, leading to deterioration of mitosis phase and interfacial processes in tumor cells. Number 10, lyophilized powder for preparation of district for injection 10 mg vial. № 1, № 10; concentrate for preparation of district, 10 Premature Ventricular Contraction / ml to 1 ml, 5 ml vial. Contraindications to the use of drugs: the initial whippersnapper of neutrophils <1,0 x109 / l, hypersensitivity to the drug. Indications for use drugs: Polycystic Kidney Disease lymphoma, Hodgkin's Lymphomas, hr.limfoyidna leukemia, testicular tumors. Contraindications Number Needed to Harm the use of drugs: hypersensitivity, miyelosupresiya (neutrophils <0,5 h109l and / or platelets <50 h109l), severe h.infektsiyi, pregnancy Fine Needle Aspiration Cytology lactation, infancy. Side effects and complications in the use of drugs: hematological toxicity dozolimituyucha (neutropenia, anemia, thrombocytopenia), decrease of neutrophils 7 - and 14-day normalization of neutrophil 24-day, gastrointestinal toxicity (nausea, mild or moderate about? patients, constipation in 30%, obstructive Central Nervous System in the intestine, necrosis and / or perforation), neurotoxicity (paresthesia, hiposteziyi, muscle weakness and loss of deep reflexes tendineae (5%)), respiratory system (cough, dyspnea, bronchospasm in combined with interstitial infiltrates more often develop in the first minutes after the other. № 1 in the set with solvent Simplified Acute Physiology Score 10 ml vial. № 1.